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DeCS
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Descriptor English:
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Endodermal Sinus Tumor
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Descriptor Spanish:
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Tumor del Seno Endodérmico
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Descriptor Portuguese:
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Tumor do Seio Endodérmico
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Synonyms English:
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Yolk Sac Tumor
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Tree Number:
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C04.557.465.510.350
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Definition English:
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An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189) |
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Indexing Annotation English:
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/blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord organ/neopl term (IM)
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History Note English:
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94; was see MESONEPHROMA 1979-93; YOLK SAC TUMOR was see MESONEPHROMA 1979-93
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Allowable Qualifiers English:
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Record Number:
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31487
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Unique Identifier:
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D018240
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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